Everything about Syndrome totally explained
In
medicine and
psychology, the term
syndrome refers to the association of several clinically recognizable features,
signs (discovered by a physician),
symptoms (reported by the patient), phenomena or characteristics that often occur together, so that the presence of one feature alerts the
physician to the presence of the others. In recent decades the term has been used outside of medicine to refer to a combination of phenomena seen in association.
In technical medical language, a "syndrome" refers only to the set of detectable characteristics. A specific
disease,
condition, or
disorder may be identified as the underlying cause. Once a physical cause has been identified, the word "syndrome" is sometimes kept in the name of the disease.
The term
syndrome derives from the Greek and means literally "run together", as the features do. It is most often used when the reason that the features occur together (the
pathophysiology of the syndrome) hasn't yet been discovered. A familiar syndrome name often continues to be used even after an underlying cause has been found, or when there are a number of different primary causes that all give rise to the same combination of symptoms and signs. Many syndromes are named after the physicians credited with first reporting the association; these are "
eponymous" syndromes (see also the
list of eponymous diseases, many of which are referred to as "syndromes"). Otherwise,
disease features or
presumed causes, as well as references to
geography,
history or
poetry, can lend their names to syndromes.
A
culture-bound syndrome is a set of symptoms where there's no evidence of an underlying biological cause, and which is only recognized as a "disease" in a particular culture.
Syndromes and associated conditions
The description of a syndrome usually includes a number of
essential characteristics, which when concurrent lead to the diagnosis of the condition. Frequently these are classified as a combination of typical
major symptoms and signs - essential to the diagnosis - together with
minor findings, some or all of which may be absent. A formal description may specify the minimum number of major and minor findings respectively, that are required for the diagnosis.
In contrast to the major and minor findings which are typical of the syndrome, there may be an association with other conditions, meaning that in persons with the specified syndrome these
associated conditions occur more frequently than would be expected by chance. While the syndrome and the associated conditions may be statistically related, they don't have a clear cause and effect relationship - for example there's likely to be a separate underlying problem or
risk factor that explains the association. An example would be
Down syndrome which has the associated condition of
diabetes mellitus. A knowledge of associated conditions would dictate that they're specifically looked for in the management of the syndrome.
Case studies
One recent
case study is
Acquired Immune Deficiency Syndrome (AIDS), so named because most syndromal immune deficiencies are either genetically precoded, or secondary to either
metabolic disorders or
hematological disease.
AIDS was originally termed "Gay Related Immune Disease" (or
GRID), a name which was revised as the disease turned out to also affect heterosexuals. Several years passed after the recognition of AIDS before
HIV (human immunodeficiency virus) was first described, finally explaining the hitherto mysterious "syndrome".
SARS (severe acute respiratory syndrome) is an even more recent example of a syndrome that was later explained with the identification of a causative
coronavirus.
Further Information
Get more info on 'Syndrome'.
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